Study of the Selectivity of Insulin-Like Growth Factor-1 Receptor (IGF1R) Inhibitors
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چکیده
منابع مشابه
Study of the Selectivity of Insulin-Like Growth Factor-1 Receptor (IGF1R) Inhibitors
The insulin-like growth factor-1 receptor (IGF1R) is a drug target for oncology, and many studies are ongoing to identify compounds that inhibit its tyrosine kinase activity. IGF1R is highly homologous to the insulin receptor (IR) and IGF1R inhibition might be beneficial for patients, while IR inhibition may lead to limiting toxicity. Therefore selectivity for IGF1R over IR is the aim for drug ...
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ژورنال
عنوان ژورنال: The Open Enzyme Inhibition Journal
سال: 2014
ISSN: 1874-9402
DOI: 10.2174/1874940201003010027